Blood rheology and proliferative retinopathy in sickle cell-haemoglobin C disease.
نویسندگان
چکیده
منابع مشابه
Blood rheology and proliferative retinopathy in sickle cell-haemoglobin C disease.
Haematological and rheological (plasma and serum viscosity, whole blood viscosity, and erythrocyte filterability) factors were studied in 31 age-sex matched pairs of patients with sickle cell haemoglobin C disease with and without proliferative sickle retinopathy (PSR). Patients with PSR had significantly higher mean cell haemoglobin and lower Hb F levels on average than the matched controls, b...
متن کاملBlood rheology and proliferative retinopathy in homozygous sickle cell disease.
Some haematological and rheological features were compared in 27 age and sex matched pairs of patients (15 male, 12 female) with homozygous sickle cell (SS) disease with and without proliferative sickle retinopathy (PSR). Significant haematological differences between the groups were a higher haemoglobin and a lower fetal haemoglobin in PSR positive males and a higher MCHC in PSR positive femal...
متن کاملEffect of Age on Blood Rheology in Sickle Cell Anaemia and Sickle Cell Haemoglobin C Disease: A Cross-Sectional Study
OBJECTIVES Blood rheology plays a key role in the pathophysiology of sickle cell anaemia (SS) and sickle cell haemoglobin C disease (SC), but its evolution over the lifespan is unknown. MATERIALS AND METHODS Blood viscosity, red blood cell (RBC) deformability and aggregation, foetal haemoglobin (HbF) and haematocrit were measured in 114 healthy individuals (AA), 267 SS (161 children + 106 adu...
متن کاملSevere proliferative retinopathy is associated with blood hyperviscosity in sickle cell hemoglobin-C disease but not in sickle cell anemia.
Little is known about the impact of blood rheology on the occurrence of retinopathy in sickle cell disease (SCD). Fifty-nine adult SCD patients in steady-state condition participated to the study: 32 with homozygous SCD (sickle cell anemia; SCA) and 27 with sickle cell hemoglobin-C disease (SCC). The patients underwent retinal examination and were categorized according to the classification of ...
متن کاملSickle-cell haemoglobin C disease in London.
The manifestations of the sickling disorders are becoming increasingly familiar to clinicians in Great Britain. One of these disorders, sickle-cell haemoglobin disease, has hitherto received little attention, being regarded as a relatively mild condition. This paper describes some of the distinctive clinical features of the disease as seen in a series of nine cases which have recently presented...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1984
ISSN: 0007-1161
DOI: 10.1136/bjo.68.5.325